A physician-directed practice for the whole picture — hormones, metabolism, labs, and the questions you’d otherwise be answering for yourself at 11pm.
4 min · Prescribed only when rightTakes about 4 minutes · Prescribed only when clinically right
The 24-week protocol
The biology · What changed
Estradiol −90% post-menopause
~1% lean mass / year after 40
Insulin sensitivity −20%
AM peak blunted, PM elevated
Slow-wave sleep −50%
Thermoneutral zone narrows
Reward circuits hyperactive
Leptin resistance rises
1–2% BMD loss / year
The labs your PCP ordersmeasure for different conditions.
The arc · 4 chapters
Week 01 Initiation
Week 06 Steady state
Week 12 Midpoint
Week 24 Maintenance
The Reset doesn’t target the scale. It targets the biology underneath the symptoms you’re already experiencing — and the functional age that biology adds to your chronological one.
Current functional age
Week 24 projection
−10 years in functional age 4 symptoms addressed
The Reset combines hormone therapy, GLP-1, biomarker labs, and coached training — sequenced for the body you have now.
Projected from aggregated GLP-1 + HRT clinical literature in perimenopausal cohorts; individual results depend on eligibility, adherence, and biology — not guaranteed.
Takes about 4 minutes.
CertifiedLegitScript healthcare
Weightstry is LegitScript-certified. Verify
Every member is matched with a physician and a registered dietitian.
Matched by license, specialty, and clinical fit — not by who is free.
Lipids, hormones, metabolic and inflammatory markers drawn at intake.
Re-drawn at week 12 and week 24. Tracked, not assumed.
State-licensed U.S. compounding pharmacy dispenses every prescription.
Active ingredient, lot, and pharmacy named on the Transparency Card.
No volume targets.
No five-minute consults.
Every protocol clinician-reviewed before dispense.
01Input/output
At 35, eating less and moving more produced response within weeks. After 42, the same inputs produce smaller, slower outputs — sometimes none at all.
02Discipline
The brain on shifting estrogen and rising cortisol isn't the brain that powered through Whole30 in your thirties.
03Visibility
The five-marker panel your GP runs at your annual physical isn't designed to surface what changed. Your numbers come back normal while you don't feel normal.
If most of this sounds like you, the 4-minute screening is the next step.
Takes about 4 minutes.
MembershipWhat’s included
Membership
Membership only. Medication priced separately.
Included in membership
Named board-certified physician, matched at intake
Biannual lab panels via Quest and Labcorp
Registered dietitian, ongoing relationship
Coach, weekly touchpoint
Daily clinical telemetry, reviewed by your care team
The Practice Hub access
All clinician messaging and protocol adjustments
Priced by the pharmacy
Terms
3-month minimum on membership. Cancel anytime after. 24-week medication commitment available as an opt-in patient discount.
LegitScript certifiedVerify
Takes about 4 minutes.
Every shipment ships with a Transparency Card. Active ingredient, concentration, vehicle, lot, pharmacy, FDA status. Your provider walks you through each field before your first dose.
Sample card — sent with every shipment
This card accompanies every shipment. Questions about compounding, concentration, or alternatives: 24/7 clinical support line.
Three HRT formulations and two GLP-1 protocols. Your physician matches what your biology actually needs — estradiol patch, micronized progesterone, testosterone cream, semaglutide, tirzepatide — titrated against labs drawn at baseline and month three. Each prescription is compounded by a 503A pharmacy, labeled with your name and lot number, and ships with a Transparency Card.
Estradiol patch, progesterone capsule, optional testosterone cream. Sequenced to your stage.
Semaglutide or tirzepatide. Matched at baseline, escalated by response.
Every Weightstry member is matched with a board-certified obesity medicine physician and a registered dietitian. We don’t list our clinicians publicly. They’re matched to you when you screen — by license, specialty, and clinical fit.
“In the STEP-1 trial4, participants on semaglutide achieved an average of 0.0% body weight loss at 68 weeks. In SURMOUNT-15, participants on tirzepatide achieved 0.0% at 72 weeks.”
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